A priori interconnect prediction and technology extrapolation are closely intertwined. Interconnect predictions are at the core of technology extrapolation models of achievable system power, area density, and speed. Technology extrapolation, in turn, informs a priori interconnect prediction via models of interconnect technology and interconnect optimizations. In this paper, we address the linkage between a priori interconnect prediction and technology extrapolation in two ways. First, we describe how rapid changes in technology, as well as rapid evolution of prediction methods, require a dynamic and flexible framework for technology extrapolation. We then develop a new tool, the GSRC technology extrapolation system (GTX), which allows capture of such knowledge and rapid development of new studies. Second, we identify several "nontraditional" facets of interconnect prediction and quantify their impact on key technology extrapolations. In particular, we explore the effects of interconnect design optimizations such as shield insertion, repeater sizing and repeater staggering, as well as modeling choices for RLC interconnects.